Characterization of patients using warfarin in relation to functional health literacy and identification of associated factors

Main Article Content

Gustavo Chaves de Souza
Carla Jorge Machado
Mayara Oliveira Ortiz
Maria Auxiliadora Parreiras Martins
Josiane Moreira da Costa

Abstract

Low functional health literacy in patients on warfarin anticoagulation has been widely discussed in the literature. Objective: To identify the quality of oral anticoagulation over time and to analyze the association between this variable and functional health literacy. Prospective cohort study conducted in an anticoagulation clinic in Minas Gerais, at a high complexity hospital. The study included 81 patients, whose data were collected through direct consultation of medical records or by asking questions during the waiting period for appointments. The quality of oral anticoagulation was assessed at 6, 9, 12, 15, and 18 months after the start of the study, with analyses of the association between this variable and functional health literacy at different time points. The quality of oral anticoagulation was identified by calculating the Therapeutic Time Range (TTR), with good quality defined as TTR values >59%. Inadequate control of oral anticoagulation was observed, with only 20% of patients showing persistent improvement in TTR values over the study period. No statistically significant association was found at different measurement times between TTR and functional health literacy. There was no direct association between the quality of oral anticoagulation and functional health literacy. However, the low incidence of persistence in anticoagulation quality among patients with low literacy suggests the need for specific educational interventions for this subgroup of patients.

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How to Cite
Chaves de Souza, G., Machado, C. J., Oliveira Ortiz, M., Parreiras Martins, M. A., & Moreira da Costa, J. (2025). Characterization of patients using warfarin in relation to functional health literacy and identification of associated factors. Revista Brasileira Multidisciplinar, 28(2), e-20252247. https://doi.org/10.25061/2527-2675/ReBraM/2025.v28i2.2247
Section
Artigos Originais
Author Biographies

Gustavo Chaves de Souza, a:1:{s:5:"pt_BR";s:8:"UNIFENAS";}

Acadêmico de Medicina da Universidade Professor Edson Antônio Velano.

Carla Jorge Machado, UFMG

Ph.D. pela Universidade Johns Hopkins/EUA (Bloomberg School of Public Health). Professora Titular no Departamento de Medicina Preventiva e Social da Faculdade de Medicina da Universidade Federal de Minas Gerais (UFMG).

Mayara Oliveira Ortiz, UFVJM

Farmacêutica pela UFMG e pós-graduada em Farmácia Clínica e Oncológica.

Maria Auxiliadora Parreiras Martins, UFMG

Doutora em Ciências da Saúde: Infectologia e Medicina Tropical pela Faculdade de Medicina da UFMG e pós-doutorado pela Boston University, Estados Unidos. Professora Associada do Departamento de Produtos Farmacêuticos da Faculdade de Farmácia da UFMG.

Josiane Moreira da Costa, UFVJM

Doutora em Medicamentos e Assistência Farmacêutica, pela Faculdade de Farmácia da UFMG. Professora adjunta do Departamento de Farmácia da Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM).

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